New Treatments for Skin Cancer
New Treatments for Skin Cancer What’s New in Basal and Squamous Cancer Research? Investigation of the causes, prevention, and treatment of basal and squamous skin cancers occurs in many medical centers around the world.
Basic skin cancer research
In recent years, scientists have made great strides in learning how ultraviolet (UV) light damages DNA in normal skin cells and that it can lead to cancer cells. Researchers are working on applying this new information to strategies for preventing and treating skin cancer.
Most skin cancers can be prevented. The best way to reduce the number of skin cancers and the pain and loss of life of this disease is to educate the public about the risk factors, prevention, and detection of skin cancer. It is important that health professionals and skin cancer survivors remind others of the dangers of excessive exposure to UV rays (both from the sun and from man-made sources such as tanning beds) and from the ease with which can’t protect your skin from UV radiation.
Skin cancer can often be found early when it is more likely to heal. Monthly skin examinations and awareness of skin cancer warning signs may be useful in finding most skin cancers when they are in the early and laryngeal phase.
The American Academy of Dermatology (AAD) annually sponsors free skin cancer screenings throughout the country. Many American Cancer Associations offices closely cooperate with AAD to provide volunteers with registration, coordination and education in connection with these free evaluations. Look for information in your area about these projections or call the American Academy of Dermatology for more information.
Along with the recommendation to remain in the shadows, the American Cancer Society uses a slogan popularized in Australia as part of its skin cancer prevention message in the United States. Slip! Decanting! Slap! ®… and Wrap “is a catchy way to remember when you go out outdoors to slip on a shirt, slop on sunscreen, slap on a hat, and wrap on sunglasses to protect your eyes and sensitive skin around them.
Prevention of genital skin cancers
Almost half the deaths of this type of skin cancers, with the cells of the cell that begins in the genital region. Many of these cancers are related to infection with certain types of human papilloma virus (HPV), which can spread through intimate organ contact. Limiting intimate organ partners and using safer intimate organ practices, such as condom use, can help reduce the risk of some of these cancers.
In recent years, vaccines have become available to help protect against infection of some types of HPV. The primary purpose of the vaccine was to reduce the risk of cervical cancer but also reduce the risk of other HPV related cancers, including some types of squamous cell skin cancer.
Hemoprevention is the use of treatment to reduce cancer risk. This is likely to be more useful for people with a high risk of skin cancer, such as those with certain inborn conditions (basal cell nevus, Xeroderma pigmentosum, etc.), skin cancer history or those who have received organ transplantation, instead of people with average risk skin cancer.
Some of the most widely studied treatment so far are retinoids, which are treatment related to vitamin A. Have demonstrated some promise in reducing the risk of squamous cell cancers, but may have side effects, Including possibly causing birth defects. For this reason they are not widely used at this time, except in some people at very high risk. Other retinoid studies are underway.
Other treatment are being examined to reduce the risk of basal cell skin cancers in high-risk people. Specific treatment called via HEDGEHOG inhibitors may help some people with basal cell nevus syndrome. For example, it has been shown that the treatment Vismodegib (Erivedge) reduced the number of new basal cell carcinomas and reduced existing tumors in humans with this syndrome. The treatment has some side effects, including loss of taste and muscle cramps, which can make it difficult for some people to take every day. Further research is being done on this type of treatment and the like.
Newer approaches to diagnosing skin cancer do not require the removal of a skin sample. Examples of such “optical biopsies ” include confocal reflectance microscopy (RCM) and optical coherence tomography (OCT). These techniques are now available in some centers and are likely to become more common in the coming years.
New Treatments for Skin Cancer
Current local treatments such as surgery and radiotherapy work well for most basal and squamous cell skin cancers. Still, even some small cancers can be difficult to treat if they are in certain areas. Newer forms of surgical treatment, such as new local medicines, photodynamic therapy and laser surgery, can help reduce scar and other unwanted treatment effects. The best way to use these treatments is now explored.
Advanced Disease Treatment
Most basal and squamous cell carcinoma of the skin is found and lying in an early stage when it is likely to be infected, but some may spread to other parts of the body. These types of cancer can often be difficult to treat with current therapies such as radiation and hemotherapy.
Squamous cell cancer: Several studies test new specific treatment for advanced squamous cell rocket. The warts of these cancers often have a large amount of protein called EGFR on their surfaces, which can help them grow. Leeks targeting this protein, such as cetuksimab (Erbitux), are now being tested in clinical trials.
Basal Cell Cancer Cancer: Basal cell carcinomas are very rare to achieve an advanced stage, but when they do, these cancers can be difficult to treat. Vismodegib and Sonidegib, medicines that target the pathway through the cells in the cells, can help some people (see selective therapy for basal and squamous cell carcinoma). Other treatment that target this time are also being investigated.